IMMUNOLOGICAL STUDY ON CHICKENS VACCINATED WITH A COMBINED INACTIVATED SALMONELLA ENTERITIDIS AND NEWCASTLE DISEASE VIRUS (ND) VACCINE

Document Type : Original Article

Authors

1 Central Laboratory for Quality Control of Veterinary Biologics

2 Veterinary Serum and Vaccine Research Institute Abassia, Cairo Egypt, P.o.B.131

Abstract

Immunogenicity of a locally prepared combined inactivated oil emulsified Salmonella enteritidis and Newcastle disease virus(SE-ND)  vaccine was evaluated in 3-weeks old chickens. The immune response against single Salmonella enteritidis, Newcastle disease and combined (SE-ND) vaccines as measured by ELISA and heamagglutination inhibition (HI) test revealed no substantial differences with respect to the protective values between single and combined vaccine.The results of challenge test showed that vaccinated chickens were effectively protected against virulent strains of Salmonella enteritidis and Newcastle disease virus. The obtained results confirmed that the locally prepared combined inactivated  Salmonella enteritidis and Newcastle disease virus was safe, potent and can effectively protect chickens against Salmonella enteritidis and Newcastle disease virus infection.

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Kafrelsheikh Veterinary Medical Journal
Volume 9, Issue 2
October 2011
Pages 59-72

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