BIOCHEMICAL EFFECT OF SOME MEDICINAL HERBS ON INDUCED HEPATOTOXICITY IN RAT

Document Type : Original Article

Authors

1 Department of Biochemistry, Faculty of Veterinary Medicine, Kafrelsheikh University, Egypt

2 Department of Physiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Egypt.

3 4)Department of Veterinary Pathology, Faculty of Veterinary Medicine, Kafrelsheikh University, Egypt.

Abstract

This study was planned to clarify the biochemical effects of the ginger on CCl4-induced acute hepatotoxicity and its comparison with garlic and combination between ginger and garlic through the determination of  the following parameters in the blood and liver tissues of albino rats liver function test. The effect of ginger and garlic against CCL4 was estimated by using white albino rats (150-200 g), which divided into 5 groups of 15 rats. The result showed that CCl4 increase GGT, AST and ALT enzymatic activities, while rats received ginger and / or garlic, their liver function parameters were restored to normal levels and the best result was that group received ginger and garlic after CCL4 injection.

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Kafrelsheikh Veterinary Medical Journal
Volume 12, Issue 2
October 2014
Pages 21-38

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