EFFICACY OF DIFFERENT VACCINES AGAINST AVIAN INFLUENZA H5N1 IN DELTA REGION

Document Type : Original Article

Authors

1 Department of Poultry Diseases Faculty of Veterinary Medicine Kafrelsheikh University

2 National Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute

3 Department of Poultry, General Organization of Veterinary Services

Abstract

The present study aimed to make assessment of immune responses against avian influenza (AI) H5N1 in 14 different commercial chicken farms located in Delta region during the period from 2011- 2012 and provide evaluation of flock level immunity after vaccination with different AI vaccines. The efficacy and protection level in the vaccinated chicken layer flock has been evaluated using haemagglutination inhibition (HI) test with vaccinal antigen produced from the same type of vaccine and field antigen produced from local Egyptian field isolate . The humoral immune response in commercial layer flocks in three different governorates ( Kalubia, Monofia and Sharkia) was higher after using the vaccinal antigen than that of the field antigen . This work gave an idea about the protection against AI virus in the tested flocks which is important for reviewing the vaccination strategy where continous evaluation of the current vaccines in the face of virus evolution is a major challenge to poultry industry in Egypt.

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